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The stage is set for a fascinating top-flight contest as league leaders Arsenal welcome bottom-placed Wolverhampton Wanderers to the their home ground.

Starting Lineups

Mikel Arteta's side have introduced a trio of alterations from the side that endured a 2-1 defeat at Villa Park last weekend. William Saliba, the Swedish striker and Gabriel Martinelli all start in the starting eleven. The captain and the Spanish midfielder drop to the substitutes' bench, while the Italian defender is not involved. The centre-back is back after missing a run of games due to injury.

The visitors also make three adjustments to their starting XI after being skelped 4-1 at Molineux by United on Monday evening. The experienced full-back, the Brazilian midfielder and the South Korean forward are recalled. Ki-Jana Hoever and Arias drop to the substitutes, while Jean‐Ricner Bellegarde misses out altogether.

Confirmed Lineups

Arsenal: Raya, White, Saliba, Hincapie, Timber, Eze, Zubimendi, Rice, Saka, Gyokeres, Martinelli.
Substitutes: Arrizabalaga, Odegaard, Gabriel Jesus, Norgaard, Trossard, Madueke, Nwaneri, Merino, Lewis-Skelly.

Wolverhampton Wanderers: Johnstone, Mosquera, Agbadou, Toti Gomes, Doherty, Joao Gomes, Andre Trindade, Krejci, Wolfe, Larsen, Hwang.
Bench: Tchatchoua, Mane, Lopez, Hoever, Chirewa, Arokodare, Arias, Santiago Bueno, Jose Sa.

Referee: Robert Jones
Video Assistant Referee: John Brooks

Preamble

Welcome! And I mean, let's be honest …

The table tells a clear story. The hosts sit proudly at the pinnacle of the table, while their opponents occupy the bottom of the division.

… yet while this will be the 42nd occasion the Premier League leaders have played the team at the foot of the division – winning 30 victories from 41, with seven draws – who are responsible for two of the four all-time upsets? Indeed, Wolves, of course! Therefore, although Mikel Arteta will undoubtedly be expecting another three points, Rob Edwards must know that underdogs occasionally succeed, and anything is possible. The start is at 8pm GMT. Let's go!

^{(The remaining bottom-beats-top wins in the modern top-flight era are Oldham’s 1-0 win over Manchester United in March 1993, and Tottenham Hotspur – admittedly, a surprising one - defeating Liverpool in November 2008.)}